Postdoc in RNA and Immunology at BRIC
fuldtid
Postdoc in RNA and Immunology at BRIC
We are looking for a highly motivated and dynamic postdoc for a two year position, who is expected to commence in January 2026.
An exciting opportunity is available for a highly motivated Postdoctoral Fellow to join the laboratory of Professor Cristian Bellodi at the Biotech Research and Innovation Centre (BRIC), University of Copenhagen.
We are seeking a Postdoctoral Fellow interested in elucidating how dysregulation of RNA modifications impacts normal and malignant hematopoiesis. The successful candidate will have access to unique genetic models and state-of-the-art technologies, including advanced biochemistry, next-generation sequencing, single-cell approaches, and proteomics. These tools will be applied to dissect RNA modification–dependent pathways in the immune system at high resolution.
Information on the department can be found at: https://www.bric.ku.dk
Our research
Our research group investigates novel posttranscriptional mechanisms of gene expression control in stem and cancer cells at molecular, cellular, and organismal levels. We have uncovered key roles for RNA modifications and translational control in regulating normal and malignant stem cell function (Guzzi et al., Cell 2018; Cieśla et al., Mol Cell 2021). Building on this foundation, we are now expanding into new research directions exploring the in vivo role of RNA modifications and metabolism in development and cancer.
Our laboratory is part of the Biotech Research and Innovation Centre (BRIC), an internationally recognized research center in the strategic area of biomedicine and cancer at the University of Copenhagen, Denmark’s largest institution for education and research. We offer a vibrant and international research environment, bringing together postdocs, technical staff, PhD students, and master’s students with a shared interest in understanding how RNA epigenetics influences development and disease. As members of BRIC, our group benefits from an interdisciplinary setting with state-of-the-art core facilities, as well as access to courses, seminars, and workshops led by national and international experts in RNA biology, immunology, and cancer research.
Your job
Our team strives to uncover the posttranscriptional programs that govern hematopoietic cell fate and malignant transformation. As a postdoctoral fellow, your task will be to spearhead an innovative research project at the intersection of RNA biology and immunology. Specifically, you will:
We are looking for a highly motivated and enthusiastic scientist with the following competencies and experience:
Essential experience and skills:
The place of employment is at the BRIC, University of Copenhagen. We offer creative and stimulating working conditions in dynamic and international research environment. Our research facilities include modern laboratories and state-of-the-art core facilities (https://healthsciences.ku.dk/research/corefacilities).
Terms of employment
The average weekly working hours are 37 hours per week.
The position is a fixed-term position limited to a period of two years. The starting date is January 1st, 2026 or after agreement.
The position is covered by the Memorandum on Job Structure for Academic Staff.
Terms of appointment and payment accord to the agreement between the Ministry of Finance and The Danish Confederation of Professional Associations on Academics in the State.
Questions
For further information please contact Cristian Bellodi, cristian.bellodi@BRIC.ku.dk; www.sund.ku.dk
Foreign applicants may find this link useful: www.ism.ku.dk (International Staff Mobility).
Application procedure
Your online application must be submitted in English by clicking ‘Apply now’ below. Furthermore, your application must include the following documents/attachments – all in PDF format:
We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the abovementioned requirements.
The further process
After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the hiring committee. All applicants are then immediately notified whether their application has been passed for assessment by an unbiased assessor. Once the assessment work has been completed each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him/herself.
You can read about the recruitment process at http://employment.ku.dk/faculty/recruitment-process/
The applicant will be assessed according to the Ministerial Order no. 242 of 13 March 2012 on the Appointment of Academic Staff at Universities.
The University of Copenhagen wish to reflect the diversity of society and encourage all qualified candidates to apply regardless of personal background.
An exciting opportunity is available for a highly motivated Postdoctoral Fellow to join the laboratory of Professor Cristian Bellodi at the Biotech Research and Innovation Centre (BRIC), University of Copenhagen.
We are seeking a Postdoctoral Fellow interested in elucidating how dysregulation of RNA modifications impacts normal and malignant hematopoiesis. The successful candidate will have access to unique genetic models and state-of-the-art technologies, including advanced biochemistry, next-generation sequencing, single-cell approaches, and proteomics. These tools will be applied to dissect RNA modification–dependent pathways in the immune system at high resolution.
Information on the department can be found at: https://www.bric.ku.dk
Our research
Our research group investigates novel posttranscriptional mechanisms of gene expression control in stem and cancer cells at molecular, cellular, and organismal levels. We have uncovered key roles for RNA modifications and translational control in regulating normal and malignant stem cell function (Guzzi et al., Cell 2018; Cieśla et al., Mol Cell 2021). Building on this foundation, we are now expanding into new research directions exploring the in vivo role of RNA modifications and metabolism in development and cancer.
Our laboratory is part of the Biotech Research and Innovation Centre (BRIC), an internationally recognized research center in the strategic area of biomedicine and cancer at the University of Copenhagen, Denmark’s largest institution for education and research. We offer a vibrant and international research environment, bringing together postdocs, technical staff, PhD students, and master’s students with a shared interest in understanding how RNA epigenetics influences development and disease. As members of BRIC, our group benefits from an interdisciplinary setting with state-of-the-art core facilities, as well as access to courses, seminars, and workshops led by national and international experts in RNA biology, immunology, and cancer research.
Your job
Our team strives to uncover the posttranscriptional programs that govern hematopoietic cell fate and malignant transformation. As a postdoctoral fellow, your task will be to spearhead an innovative research project at the intersection of RNA biology and immunology. Specifically, you will:
- Define how RNA modifications regulate blood stem cells and lineage commitment
- Uncover RNA epitranscriptomic pathways driving immunity and leukemic transformation
- Explore transcriptome and translatome changes in stem cells under stress
- Optimize cutting-edge molecular profiling approaches to study hematopoietic populations
We are looking for a highly motivated and enthusiastic scientist with the following competencies and experience:
Essential experience and skills:
- PhD in Immunology, Microbiology or Molecular Biology (preferably less than two years)
- Strong background in molecular biology and biochemistry (e.g., RNA/DNA isolation, cloning, gene silencing, CRISPR gene editing, etc.)
- Hands-on experience with mouse genetics (e.g., handling, breeding, dissection, transplantation, etc.) and hematopoietic stem cell culture (murine and human);
- Expertise with advanced flow cytometry and single cell analysis;
- Active interest in the application and development of transcriptome-wide approaches to study RNA (e.g., CLIP-seq, ribosome profiling, single cell RNA-seq, PRAISE, Nanopore, etc.);
- Excellent communication skills and proven ability to work collaboratively in teams;
- Proficiency in written and spoken english;
- Experience with genome-wide gene-editing and drug screening approaches;
- Experience in quantitative proteomics and advanced microscopy methods;
- Hands-on experience with viral preparation and infection systems;
- Experience in bioinformatics, including programming in R, Python, and/or Bash, as well as familiarity with statistical analysis and high-throughput sequencing data pipelines;
- Documented experience in scientific writing, evidenced by peer-reviewed publications, fellowships, and/or prizes.
The place of employment is at the BRIC, University of Copenhagen. We offer creative and stimulating working conditions in dynamic and international research environment. Our research facilities include modern laboratories and state-of-the-art core facilities (https://healthsciences.ku.dk/research/corefacilities).
Terms of employment
The average weekly working hours are 37 hours per week.
The position is a fixed-term position limited to a period of two years. The starting date is January 1st, 2026 or after agreement.
The position is covered by the Memorandum on Job Structure for Academic Staff.
Terms of appointment and payment accord to the agreement between the Ministry of Finance and The Danish Confederation of Professional Associations on Academics in the State.
Questions
For further information please contact Cristian Bellodi, cristian.bellodi@BRIC.ku.dk; www.sund.ku.dk
Foreign applicants may find this link useful: www.ism.ku.dk (International Staff Mobility).
Application procedure
Your online application must be submitted in English by clicking ‘Apply now’ below. Furthermore, your application must include the following documents/attachments – all in PDF format:
- Motivated letter of application (max. one page).
- CV incl. education, work/research experience, language skills and other skills relevant for the position.
- A certified/signed copy of a) PhD certificate and b) Master of Science certificate. If the PhD is not completed, a written statement from the supervisor will do.
- List of publications.
We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the abovementioned requirements.
The further process
After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the hiring committee. All applicants are then immediately notified whether their application has been passed for assessment by an unbiased assessor. Once the assessment work has been completed each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him/herself.
You can read about the recruitment process at http://employment.ku.dk/faculty/recruitment-process/
The applicant will be assessed according to the Ministerial Order no. 242 of 13 March 2012 on the Appointment of Academic Staff at Universities.
The University of Copenhagen wish to reflect the diversity of society and encourage all qualified candidates to apply regardless of personal background.